Pregnant women are afraid of taking any category of drugs during the first trimester, as this period is vital for the health of the future baby and they think about the possible risks.
Fortunately, many future mothers can now be quiet about the drug Zofran. The research, held by scientists from the Institute of Sera in Copenhagen has shown that Zofran is safe during the first trimester of pregnancy and does not cause birth defects.
During the study, 608,385 pregnancies were analyzed and it set up, that the drug does not lead to an increase in the number of birth defects.
Morning sickness sometimes is very intensive and causes strong vomiting, which can lead to dehydration of the body. Nausea and vomiting in the morning may be in the first trimester of pregnancy and often require the use of drugs. Today one of the most commonly used drugs treating this symptom is Zofran. The drug is metabolized in the liver. Its half-life is 5-7 hours. Common side effects are constipation and headache.
Nowadays the use of Zofran by pregnant women has increased, and most doctors continue to prescribe it. However, Zofran was not officially approved by the FDA as a drug that was allowed during pregnancy.
That’s why the study was important, as there wasn’t absolute certainty in the safety of Zofran during pregnancy, and it is used in the early stages of pregnancy, that, according to many opinions, can lead to birth defects.
Thus, this study is intended to calm the future mothers who are currently taking this drug, and also to help to decide to become pregnant to the women who have already experienced morning sickness in the past.
It is also important, that if you need to use the drug during lactation, you should consult your doctor and discuss the interruption of breastfeeding.